A dermatofibroma is defined as a benign fibrous nodule that mainly affects the skin on the lower legs. It occurs in all age groups. However, the prevalence is higher in women than in men.

It has not been established yet if dermatofibroma should be classified as neoplasm or simply a reactive process. These lesions are made up of proliferating fibroblasts. Histocytes can also play a role.

Dermatofibroma usually develops in the areas of legs and arms, but can also affect the trunk and other body sites.

The clinical features of dermatofibroma are quite distinct. Affected individuals on average have from 1 to 15 lesions. The size of a lesion can vary from 0.5 to 1.5 cm, but the majority of lesions are from 7 to 10 mm in diameter.  They appear as immovable firm nodules on the surface of the skin and as mobile nodules in the subcutaneous tissue. The color may appear as pink or light brown on fair skin and as dark brown or black on darker skin. The lesions are usually asymptomatic, but some patients report experiencing pain and itching.

Since dermatofibroma can appear as a raised lesion, it can be easily traumatized on daily basis and during everyday activities (e.g. by a razor).

Quite often, dozens of dermatofibroma lesions can erupt within a couple of months due to immunosuppression, such as medications, cancer, or autoimmune disease.

Dermatofibroma does not progress into cancer. However, in some cases, it can be mistaken for desmoplastic melanoma.

Dermatofibroma is easy to diagnose due to its distinct features. The examination is usually done via dermatoscopy. The most commonly observed dermatoscopic pattern is a central white area that is surrounded by a lightly pigmented network. The skin biopsy or diagnostic excision can be done if atypical features like ulceration, enlargement, or asymmetrical structures are observed during examination.

A dermatofibroma is a harmless skin lesion and does not present any symptoms. The lesion can be removed surgically if it causes discomfort or concern however it has a tendency to reoccur.

Cryotherapy, laser, and shave biopsy can be incorporated into treatment to reduce dermatofibroma.

Centre for Medical and Surgical Dermatology offers unique and personalized dermatofibroma treatment options for each patient.